Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3294305 | 0.98 | CHKA (0.53) | CHKAALDH1A1SMN1; SMN2LMNAHTT | |
| SCHEMBL28278790 | 0.82 | CA2 (0.58) | SMN1; SMN2KMT2APRSS1F2FAAH | |
| SCHEMBL92893 | 0.82 | CA2 (0.58) | SMN1; SMN2KMT2APRSS1F2FAAH | |
| Bromide SCHEMBL28167961 | 0.80 | CA2 (0.56) | SMN1; SMN2KMT2APRSS1F2FAAH | |
| Sulfuric Acid SCHEMBL28325623 | 0.77 | PRSS1 (0.52) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL28195609 | 0.77 | CA2 (0.52) | ALDH1A1KMT2APRSS1F2FAAH | |
| SCHEMBL5304667 | 0.77 | TP53 (0.64) | CHKAALDH1A1SMN1; SMN2LMNAHTT | |
| Chloroform SCHEMBL28290993 | 0.75 | PRSS1 (0.50) | ALDH1A1HTTMEN1KMT2APRSS1 | |
| Carbon Tetrachloride SCHEMBL28292391 | 0.75 | PRSS1 (0.50) | KMT2APRSS1F2FAAHPRSS2 | |
| Hydrochloric Acid SCHEMBL5155076 | 0.75 | ALDH1A1 (0.61) | CHKAALDH1A1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263720-B1 | AZETIDINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2009-06-03 | — | — | EP | disclosed |
| EP-1263720-A1 | AZETIDINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001064632-A1 | AZETIDINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2001-09-07 | — | — | WO | disclosed |