SCHEMBL4028081

SCHEMBL4028081

O=C1CNCCN1CCCO

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 1/20 0.33
PABPC1 P11940 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
F10 P00742 1/20 0.31
SCN9A Q15858 1/20 0.31
USP2 O75604 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GSK3A P49840 1/20 0.31
GSK3B P49841 1/20 0.31
USP19 O94966 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL978058 0.89 KMT2A (0.35) KMT2AF10SCN9AUSP19MEN1
Hydrochloric Acid SCHEMBL3999990 0.87 KMT2A (0.34) KMT2ASCN9AUSP19MEN1
SCHEMBL5337457 0.84 JAK2 (0.34) F10USP19
SCHEMBL1583265 0.81 MEN1 (0.49) KMT2AALDH1A1L3MBTL1TSHRHSD17B10
SCHEMBL22123100 0.81 CXCR4 (0.33) KMT2AF10MEN1
SCHEMBL8486724 0.80
Bromide SCHEMBL28431073 0.80 MEN1 (0.47) KMT2AALDH1A1L3MBTL1TSHRHSD17B10
SCHEMBL19980682 0.80 CXCR4 (0.35) F10
SCHEMBL27789194 0.80 F10 (0.31) F10
SCHEMBL161338 0.80 MEN1 (0.43) KMT2AALDH1A1TSHRHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115646137-B Organic amine desulfurizing agent capable of effectively reducing foaming problem 北京北大先锋科技股份有限公司 2026-05-12 CN claimed
CN-115646137-A Organic amine desulfurizer capable of effectively reducing foaming problem 北京北大先锋科技股份有限公司 2023-01-31 CN claimed
CN-115646137-B Organic amine desulfurizing agent capable of effectively reducing foaming problem 北京北大先锋科技股份有限公司 2026-05-12 CN disclosed
CN-115646137-A Organic amine desulfurizer capable of effectively reducing foaming problem 北京北大先锋科技股份有限公司 2023-01-31 CN disclosed
CN-112973419-A Proportion-controllable composite hydroxyalkyl piperazine desulfurizer as well as preparation method and application thereof 合肥工业大学 2021-06-18 CN disclosed
EP-1528925-B1 QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2009-04-22 EP disclosed
US-7504408-B2 Quinzoline derivatives for use in the treatment of cancer ASTRAZENECA AB (SE) 2009-03-17 US disclosed
US-20050250797-A1 Quinzoline derivatives for use in the treatment of cancer ASTRAZENECA AB (SE) 2005-11-10 US disclosed
EP-1528925-A1 QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER Astrazeneca AB (SE) 2005-05-11 EP disclosed
WO-2004004732-A1 QUINAZOLINE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2004-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050250797-A1 Quinzoline derivatives for use in the treatment of cancer TPD52L2, NQO2, CCNI KMT2A 706/4885ALDH1A1 1137/4885PABPC1 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.