SCHEMBL5337457

SCHEMBL5337457

O=C1CNCCN1CCN1CCNCC1=O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.34
JAK1 P23458 1/20 0.34
TYK2 P29597 1/20 0.34
JAK3 P52333 1/20 0.34
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
USP19 O94966 1/20 0.31
F10 P00742 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11630025 0.90 SMN1; SMN2 (0.42) POLBSMN1; SMN2
SCHEMBL8618294 0.88 DRD2 (0.37) POLBSMN1; SMN2
SCHEMBL1583740 0.87 MEN1 (0.35) JAK2JAK1TYK2JAK3POLB
SCHEMBL4340726 0.87 ALOX15 (0.31) F10
SCHEMBL7359626 0.87
SCHEMBL3340135 0.87 F10 (0.30) F10
SCHEMBL12629399 0.87
SCHEMBL1176767 0.87 ALDH1A1 (0.30) POLB
SCHEMBL978058 0.87 KMT2A (0.35) USP19F10
Hydrochloric Acid SCHEMBL1570926 0.87 DRD2 (0.36) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7235282-B2 Restoration of discolored surfaces of structures of a vinyl chloride polymer by treating in ambient air with an organic solution comprising an organic peroxide and an organic solvent, e.g., whitening of a susrface made pink by weathering; well suited to the treatment of sheeting and profiles SOLVAY (SOCIETE ANONYME) (BE) 2007-06-26 US disclosed
US-20040234700-A1 Method of treating the surface of aged objects with polyvinyl chloride SOLVAY (SOCIETE ANONYME) (BE) 2004-11-25 US disclosed