Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026109 | 0.91 | MAPT (0.40) | MAPTALDH1A1HPGDLMNAALOX15 | |
| SCHEMBL5109466 | 0.89 | MAPT (0.37) | MAPTALDH1A1HPGDLMNARAB9A | |
| SCHEMBL5109472 | 0.89 | MAPT (0.37) | MAPTALDH1A1HPGDLMNARAB9A | |
| SCHEMBL4022141 | 0.84 | MAPT (0.40) | MAPTALDH1A1HPGDLMNARAB9A | |
| SCHEMBL4021051 | 0.79 | ALOX15 (0.44) | ALDH1A1LMNAALOX15NPSR1 | |
| SCHEMBL6594999 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDLMNAALOX15 | |
| SCHEMBL6594995 | 0.78 | ALDH1A1 (0.46) | MAPTALDH1A1HPGDLMNAALOX15 | |
| SCHEMBL3557099 | 0.76 | MAPT (0.38) | MAPTALDH1A1HPGDLMNARAB9A | |
| SCHEMBL3557097 | 0.76 | MAPT (0.38) | MAPTALDH1A1HPGDLMNARAB9A | |
| SCHEMBL5335807 | 0.72 | MAPT (0.36) | MAPTALDH1A1HPGDLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485375-B1 | PYRIMIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2009-06-17 | — | — | EP | disclosed |