Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | KIF11 | P52732 | 4/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022303 | 0.89 | KDM2B (0.34) | KDM2BMGLLMEN1KMT2AKIF11 | |
| SCHEMBL4024473 | 0.85 | ABL1 (0.37) | KDM2BMGLLMEN1KMT2AKIF11 | |
| SCHEMBL4024477 | 0.85 | ABL1 (0.37) | KDM2BMGLLMEN1KMT2AKIF11 | |
| SCHEMBL4029041 | 0.85 | KDM4E (0.38) | KDM2BMGLLMEN1KMT2AOPRD1 | |
| SCHEMBL4749303 | 0.84 | KDM2B (0.31) | KDM2BKIF11 | |
| SCHEMBL4749084 | 0.84 | KDM2B (0.31) | KDM2BKIF11 | |
| SCHEMBL4749092 | 0.84 | KDM2B (0.31) | KDM2BKIF11 | |
| SCHEMBL4749288 | 0.84 | KDM2B (0.31) | KDM2BKIF11 | |
| SCHEMBL4020633 | 0.83 | MEN1 (0.35) | KDM2BMGLLMEN1KMT2AOPRD1 | |
| SCHEMBL4024540 | 0.83 | MEN1 (0.35) | KDM2BMGLLMEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |