Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 7/20 | 0.34 |
| ▸ | MGLL | Q99685 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028130 | 0.89 | KDM2B (0.35) | KDM2BMGLLMEN1KMT2ASLC2A1 | |
| SCHEMBL4752190 | 0.89 | KDM2B (0.34) | KDM2BMGLL | |
| SCHEMBL4028319 | 0.87 | KDM2B (0.43) | KDM2BMEN1KMT2A | |
| SCHEMBL4778094 | 0.87 | KDM2B (0.32) | KDM2B | |
| SCHEMBL4024173 | 0.87 | KDM2B (0.33) | KDM2BMGLLMEN1KMT2A | |
| SCHEMBL4749457 | 0.86 | — | — | |
| SCHEMBL4021957 | 0.86 | KDM2B (0.32) | KDM2BMGLLMEN1KMT2A | |
| SCHEMBL4024540 | 0.86 | MEN1 (0.35) | KDM2BMGLLMEN1KMT2ASLC2A1 | |
| SCHEMBL4020633 | 0.86 | MEN1 (0.35) | KDM2BMGLLMEN1KMT2ASLC2A1 | |
| SCHEMBL13720775 | 0.86 | MEN1 (0.35) | KDM2BMGLLMEN1KMT2ASLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |