Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022303 | 0.87 | KDM2B (0.34) | KDM2BKMT2AMEN1 | |
| SCHEMBL4021398 | 0.87 | KDM2B (0.45) | KDM2BKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL4024597 | 0.87 | KDM2B (0.45) | KDM2BKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL4751398 | 0.85 | KMT2A (0.47) | KDM2BKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL4022832 | 0.85 | KDM2B (0.43) | KDM2BKMT2AHTTMEN1NPSR1 | |
| SCHEMBL13721307 | 0.85 | KDM2B (0.43) | KDM2BKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL4018780 | 0.85 | KDM2B (0.43) | KDM2BKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL4027956 | 0.85 | KDM2B (0.43) | KDM2BKMT2AHTTALDH1A1MEN1 | |
| SCHEMBL4029178 | 0.85 | KDM2B (0.43) | KDM2BKMT2AHTTMEN1NPSR1 | |
| SCHEMBL4018783 | 0.85 | KDM2B (0.43) | KDM2BKMT2AHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |