SCHEMBL4028936

SCHEMBL4028936

CC[Si](CC)(CC)N(C)C(=O)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.35
CHRM4 P08173 4/20 0.35
CHRM5 P08912 4/20 0.35
CHRM1 P11229 4/20 0.35
CHRM3 P20309 4/20 0.35
FAAH O00519 8/20 0.32
CES1 P23141 5/20 0.31
CES2 O00748 2/20 0.31
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29368701 0.85 FAAH (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL29367428 0.84 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL29365529 0.82 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL29368734 0.81 FAAH (0.39) FAAHCES1CES2MEN1CYP1A2
SCHEMBL9108572 0.81 FAAH (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL17926685 0.77 CHRM2 (0.31) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL29367409 0.76 FAAH (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL23035533 0.75 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL11270523 0.75 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL231141 0.75 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111886676-B Method for treating surface of wafer and composition therefor 中央硝子株式会社 2024-09-27 CN claimed
US-12416028-B2 Biosynthetic production of gamma- and delta-lactones using cytochrome P450 enzymes having subterminal hydroxylase activity CONAGEN INC. (US) 2025-09-16 US disclosed
CN-111742391-B Chemical solution for forming water-repellent protective film, method for producing same, and method for producing surface-treated body 中央硝子株式会社 2025-02-18 CN disclosed
US-12098319-B2 Liquid chemical for forming water-repellent protective film, method for preparing same, and method for manufacturing surface-treated body CENTRAL GLASS COMPANY, LIMITED (JP) 2024-09-24 US disclosed
CN-113557259-B Biosynthesis of gamma-and delta-lactones using cytochrome P450 enzymes with subterminal hydroxylase activity 科纳根公司 2024-03-08 CN disclosed
US-20230387464-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MU IONIC SOLUTIONS CORPORATION (JP) 2023-11-30 US disclosed
US-20230387464-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MU IONIC SOLUTIONS CORPORATION (JP) 2023-11-30 US disclosed
US-11670498-B2 Surface treatment agent and surface-treated body manufacturing method CENTRAL GLASS COMPANY, LIMITED (JP) 2023-06-06 US disclosed
US-20230125746-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MITSUBISHI CHEMICAL CORPORATION (JP) 2023-04-27 US disclosed
US-20230125746-A1 Nonaqueous Electrolytic Solution and Nonaqueous Electrolytic Solution Battery MITSUBISHI CHEMICAL CORPORATION (JP) 2023-04-27 US disclosed
EP-1165552-A1 C7 CARBONATE SUBSTITUTED TAXANES AS ANTITUMOR AGENTS Florida State University Research Foundation, Inc. (US) 2002-01-02 EP disclosed
EP-0956284-A4 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES UNIV FLORIDA STATE (US) 2001-12-05 EP disclosed
US-6291691-B1 CONVERTING THE C(7) HYDROXY GROUP OF A 10-ACYLOXY-9-OXO-7-HYDROXYTAXANE TO AN ACETAL OR KETAL, BY REACTING WITH KETALIZING AGENT IN PRESENCE OF AN ACID CATALYST TO FORM FLORIDA STATE UNIVERSITY 2001-09-18 US disclosed
WO-2001057027-A1 C7 ESTER SUBSTITUTED TAXANES AS ANTITUMOR AGENTS FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2001-08-09 WO disclosed
WO-2001057030-A1 C7 CARBONATE SUBSTITUTED TAXANES AS ANTITUMOR AGENTS FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2001-08-09 WO disclosed
US-6191287-B1 TREATING THE TAXANE WITH A SILYAMIDE OR A BISSILYLAMIDE TO FORM C10 SILYLATED TAXANE FLORIDA STATE UNIVERSITY 2001-02-20 US disclosed
CN-1239476-A Process for selective derivatization of taxanes UNIV FLORIDA STATE (US) 1999-12-22 CN disclosed
EP-0956284-A1 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES Florida State University (US) 1999-11-17 EP disclosed
WO-1999009021-A1 PROCESS FOR SELECTIVE DERIVATIZATION OF TAXANES FLORIDA STATE UNIVERSITY (US) 1999-02-25 WO disclosed
EP-0589914-A1 NOVEL 3-FUSED PYRIDINIUMMETHYL CEPHALOSPORINS CHEIL FOODS & CHEMICALS, INC. (KR) 1994-04-06 EP disclosed