Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 5/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028936 | 0.81 | CHRM2 (0.35) | FAAHCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL50594 | 0.72 | CHRM2 (0.34) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29367428 | 0.70 | CHRM2 (0.34) | FAAHCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4353256 | 0.69 | ALDH1A1 (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL29365529 | 0.68 | CHRM2 (0.33) | FAAHCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL249531 | 0.67 | MLYCD (0.45) | FAAHCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8775960 | 0.67 | ALOX15 (0.32) | — | |
| SCHEMBL29368701 | 0.67 | FAAH (0.33) | FAAHCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL8144791 | 0.67 | — | — | |
| SCHEMBL26430616 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638078-A4 | AVERMECTIN DIFLUORO DERIVATIVES. | — | 1995-03-22 | — | — | EP | disclosed |