Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941340 | 0.81 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL3941342 | 0.81 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL4035891 | 0.81 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL4035886 | 0.81 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL3946267 | 0.77 | KCNH2 (0.40) | KCNH2CYP8B1 | |
| SCHEMBL3946262 | 0.77 | KCNH2 (0.40) | KCNH2CYP8B1 | |
| SCHEMBL3944928 | 0.77 | CYP8B1 (0.37) | KCNH2CYP8B1 | |
| SCHEMBL1224745 | 0.73 | KCNH2 (0.38) | KCNH2CYP8B1 | |
| SCHEMBL1224748 | 0.73 | KCNH2 (0.38) | KCNH2CYP8B1 | |
| SCHEMBL1223261 | 0.72 | ALDH1A1 (0.45) | KCNH2CYP8B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034546-A2 | TRANS-DECAHYDROISOQUINOLINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-03-19 | — | — | WO | disclosed |