Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.51 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187746 | 0.89 | MGLL (0.59) | MGLLARNPC1HPGDRAB9A | |
| SCHEMBL5691423 | 0.89 | AR (0.56) | MGLLARNPC1HPGDRAB9A | |
| SCHEMBL5757576 | 0.88 | MGLL (0.61) | MGLLARNPC1HPGDRAB9A | |
| SCHEMBL8889394 | 0.87 | MGLL (0.64) | MGLLARNPC1HPGDRAB9A | |
| SCHEMBL24041852 | 0.82 | CA1 (0.51) | NPC1RAB9AFFAR1CA12CA1 | |
| SCHEMBL20294565 | 0.82 | ALDH1A1 (0.45) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL3438747 | 0.82 | POLB (0.47) | HPGDCA1CA2CA9 | |
| SCHEMBL5277439 | 0.82 | CA1 (0.49) | MGLLARNPC1HPGDRAB9A | |
| SCHEMBL4167398 | 0.81 | MGLL (0.49) | MGLLARNPC1HPGDRAB9A | |
| SCHEMBL24041893 | 0.81 | FFAR1 (0.57) | MGLLNPC1RAB9AFFAR1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |