Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026184 | 0.80 | FFAR1 (0.60) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL4030641 | 0.77 | BCHE (0.56) | BCHEPPARAPPARGPPARDRAB9A | |
| SCHEMBL28686580 | 0.76 | BCHE (0.61) | BCHEMMP12FFAR1FFAR4LTA4H | |
| SCHEMBL4025982 | 0.75 | PPARG (0.46) | PPARAPPARGHPGD | |
| SCHEMBL4030084 | 0.75 | PPARG (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5921 | 0.75 | LMNA (0.57) | BCHEPPARAPPARGPPARDMMP12 | |
| SCHEMBL4026024 | 0.75 | LTA4H (0.56) | BCHEPPARAPPARGPPARDMMP12 | |
| SCHEMBL5853921 | 0.74 | CA1 (0.39) | PPARAPPARGARNPC1HPGD | |
| SCHEMBL5988741 | 0.74 | PPARA (0.53) | BCHEPPARAPPARGPPARDAR | |
| SCHEMBL5691423 | 0.73 | AR (0.56) | BCHEARNPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569916-B1 | SUBSTITUTED ARALKYL DERIVATIVES | CADILA HEALTHCARE LTD (IN) | 2009-01-07 | — | — | EP | claimed |