Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 4/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 4/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.38 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | POLQ | O75417 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3823273 | 0.81 | CCNC (0.38) | MAPTKDM4ESMARCA2SMARCA4CCNC | |
| SCHEMBL4028773 | 0.80 | MAPT (0.53) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL2761348 | 0.80 | MAPT (0.51) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL4030049 | 0.80 | MAPT (0.60) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL4032399 | 0.79 | LPAR1 (0.67) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL3829385 | 0.77 | POLB (0.51) | MAPTSMARCA2SMARCA4CCNCCDK8 | |
| SCHEMBL4035675 | 0.77 | MAPT (0.67) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL4034814 | 0.77 | MAPT (0.53) | MAPTKDM4ELPAR1LPAR3ABCC3 | |
| SCHEMBL12467498 | 0.76 | MAPT (0.52) | MAPTKDM4ELPAR1LPAR3LPAR2 | |
| SCHEMBL4037272 | 0.76 | MAPT (0.54) | MAPTKDM4ELPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |