Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.45 |
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935545 | 0.91 | ERAP2 (0.45) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL3940306 | 0.90 | ALOX5 (0.45) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL3941237 | 0.90 | ALOX5 (0.47) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL3944233 | 0.89 | ALOX5 (0.46) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL13912827 | 0.88 | ALOX5 (0.47) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL3944205 | 0.88 | CTSL (0.49) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL3936476 | 0.88 | ALOX5 (0.48) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL3941158 | 0.88 | ALOX5 (0.44) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL3937830 | 0.87 | ALOX5 (0.46) | ALOX5EPHX2HDAC3HDAC1HDAC2 | |
| SCHEMBL3942280 | 0.86 | ALOX5 (0.49) | ALOX5EPHX2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075987-A1 | ALKYLACETYLENE SUBSTITUTED ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AG (DE) | 2009-03-19 | — | — | US | disclosed |
| US-20090075987-A1 | ALKYLACETYLENE SUBSTITUTED ACYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AG (DE) | 2009-03-19 | — | — | US | disclosed |
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |
| EP-2019102-A1 | Alkylacetylene substituted Acyltryptophanols | Bayer Schering Pharma AG (DE) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075987-A1 | ALKYLACETYLENE SUBSTITUTED ACYLTRYPTOPHANOLS | FSHR, GNRHR, CYP19A1 | ALOX5 870/4885EPHX2 3660/4885HDAC3 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.