Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909556 | 0.87 | POLB (0.64) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5909553 | 0.87 | POLB (0.64) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL572756 | 0.83 | POLB (0.59) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3777075 | 0.83 | POLB (0.59) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3787744 | 0.83 | POLB (0.59) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4665372 | 0.83 | POLB (0.59) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL721693 | 0.83 | POLB (0.74) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27495 | 0.83 | POLB (0.59) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6519223 | 0.80 | POLB (0.61) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4200789 | 0.77 | SMN1; SMN2 (0.49) | POLBTDP1APEX1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7511110-B2 | Crosslinkable polyorganosiloxane compositions | WACKER CHEMIE AG (DE) | 2009-03-31 | — | — | US | disclosed |
| US-7385000-B2 | Silicone rubber composition having improved storage stability | WACKER CHEMIE AG (DE) | 2008-06-10 | — | — | US | disclosed |
| US-20060135689-A1 | Crosslinkable polyorganosiloxane compositions | WACKER CHEMIE GMBH (DE) | 2006-06-22 | — | — | US | disclosed |
| US-20060084745-A1 | Silicone rubber composition having improved storage stability | WACKER-CHEMIE GMBH (DE) | 2006-04-20 | — | — | US | disclosed |
| US-6359098-B1 | SHELF LIFE AS ONE-COMPONENT ADDITION-CURABLE ORGANOPOLYSILOXANES, AND EXTENDED POT LIFE FOR TWO-COMPONENT ADDITION-CURABLE ORGANOPOLYSILOXANES, WITHOUT COMPROMISING CROSSLINKING RATES OR LEVELS | WACKER-CHEMIE GMBH (DE) | 2002-03-19 | — | — | US | disclosed |