Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031075 | 1.00 | PPARG (0.50) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4030069 | 0.88 | PPARG (0.55) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4854412 | 0.87 | PPARG (0.51) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4854473 | 0.87 | PPARG (0.51) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6584580 | 0.83 | FDPS (0.57) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6583683 | 0.83 | FDPS (0.57) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4029301 | 0.80 | PPARG (0.53) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4852715 | 0.80 | PPARG (0.49) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4852732 | 0.80 | PPARG (0.49) | PPARGMAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4846344 | 0.79 | PPARG (0.52) | PPARGMAPTKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357115-B1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2009-06-17 | — | — | EP | disclosed |
| EP-1357115-A1 | ALKANOIC ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |