Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584580 | 1.00 | FDPS (0.57) | FDPSPPARGACHEBCHEMAOB | |
| SCHEMBL6961196 | 0.93 | FDPS (0.53) | FDPSPPARGKDM4EALDH1A1HPGD | |
| SCHEMBL6961189 | 0.93 | FDPS (0.53) | FDPSPPARGKDM4EALDH1A1HPGD | |
| SCHEMBL6160140 | 0.85 | PPARG (0.57) | FDPSPPARGKDM4EALDH1A1HPGD | |
| SCHEMBL8340592 | 0.84 | PPARG (0.53) | PPARGKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL8335514 | 0.84 | PPARG (0.55) | PPARGKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL6966486 | 0.84 | PPARG (0.53) | PPARGKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL6584922 | 0.84 | PPARG (0.55) | PPARGKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL4845654 | 0.84 | PPARG (0.54) | PPARGKDM4EALDH1A1HPGDLMNA | |
| SCHEMBL4031069 | 0.83 | PPARG (0.50) | FDPSPPARGKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710659-B1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-01-28 | — | — | EP | disclosed |
| US-5932601-A | USEFUL FOR LOWERING BLOOD SUGAR AND LIPID IN BLOOD | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0710659-A1 | Oxazolidinedione derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-05-08 | — | — | EP | disclosed |