Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3943591 | 0.87 | RAB9A (0.39) | RAB9ANPC1HDAC1ALDH1A1KDM4E | |
| SCHEMBL3943911 | 0.86 | RAB9A (0.40) | RAB9ANPC1C3AR1KMT2AHDAC1 | |
| SCHEMBL3942490 | 0.85 | RAB9A (0.58) | RAB9ANPC1KMT2AHDAC1HDAC6 | |
| SCHEMBL4197663 | 0.85 | RAB9A (0.58) | RAB9ANPC1KMT2AHDAC1HDAC6 | |
| SCHEMBL3943978 | 0.85 | RAB9A (0.58) | RAB9ANPC1KMT2AHDAC1HDAC6 | |
| SCHEMBL3941454 | 0.85 | RAB9A (0.58) | RAB9ANPC1KMT2AHDAC1HDAC6 | |
| SCHEMBL3944015 | 0.85 | RAB9A (0.58) | RAB9ANPC1KMT2AHDAC1HDAC6 | |
| SCHEMBL3945898 | 0.82 | ALDH1A1 (0.51) | RAB9ANPC1KMT2AALDH1A1KDM4E | |
| SCHEMBL3943464 | 0.82 | ALDH1A1 (0.44) | RAB9ANPC1KMT2AHDAC1HDAC6 | |
| SCHEMBL3945345 | 0.81 | ALDH1A1 (0.42) | RAB9ANPC1KMT2AHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | claimed |
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |