Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29546973 | 1.00 | MAPK1 (0.60) | MAPK1TSHRERN1BACE1VCAM1 | |
| SCHEMBL27623490 | 0.93 | MAPK1 (0.53) | MAPK1TSHRERN1BACE1VCAM1 | |
| SCHEMBL8806521 | 0.86 | ALDH1A1 (0.48) | MAPK1TSHRERN1BACE1VCAM1 | |
| SCHEMBL3498042 | 0.86 | TSHR (0.49) | MAPK1TSHRERN1BACE1VCAM1 | |
| SCHEMBL29708112 | 0.85 | MAPK1 (0.55) | MAPK1TSHRERN1VCAM1TDP1 | |
| SCHEMBL203086 | 0.85 | MAPK1 (0.55) | MAPK1TSHRERN1VCAM1TDP1 | |
| SCHEMBL6782825 | 0.83 | TSHR (0.46) | MAPK1TSHRERN1BACE1VCAM1 | |
| SCHEMBL16961813 | 0.83 | MAPK1 (0.58) | MAPK1TSHRBACE1VCAM1LMNA | |
| SCHEMBL16952297 | 0.83 | MAPK1 (0.58) | MAPK1TSHRBACE1VCAM1TDP1 | |
| SCHEMBL6377970 | 0.83 | MAPK1 (0.58) | MAPK1TSHRBACE1VCAM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1003 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110590561-B | Herbicidal ether hapten, artificial antigen and antibody as well as preparation method and application thereof | 北京勤邦生物技术有限公司 | 2022-08-19 | — | — | CN | claimed |
| US-20220257483-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2022-08-18 | — | — | US | claimed |
| EP-4003286-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | Henkel AG & Co. KGaA (DE) | 2022-06-01 | — | — | EP | claimed |
| CN-114173750-A | Improving the stability of agents for treating keratin materials | 汉高股份有限及两合公司 | 2022-03-11 | — | — | CN | claimed |
| CN-109651189-B | Benzoyl hydrazone neuraminidase inhibitor and preparation method and application thereof | 上海应用技术大学 | 2021-11-19 | — | — | CN | claimed |
| WO-2021013420-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | HENKEL AG & CO. KGAA (DE) | 2021-01-28 | — | — | WO | claimed |
| CN-107522766-B | Ursolic acid quinolyl hydrazide derivatives with anti-tumor activity and preparation method and application thereof | 南京林业大学 | 2020-03-27 | — | — | CN | claimed |
| US-20130190500-A1 | PROCESS TO PREPARE 6-CHLORO-3-AMINO-2-(2-HYDROXYPROPYL)-1-AZANAPHTHALENE | NEURON SYSTEMS, INC. (US) | 2013-07-25 | — | — | US | claimed |
| CN-102659611-A | Method for preparing 2-amino-5-chloro-2',6'-difluorobenzophenone | ZHEJIANG QIMING BIOCHEMICAL TECHNOLOGY CO LTD | 2012-09-12 | — | — | CN | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| WO-2003030845-A1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300133-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| US-6448413-B1 | 17-HYDROXY-17-METHYL-1,3-SECO-2-NOR-5-ANDROSTANE-3-ACID DERIVATIVES FROM MESTANOLONE AND AROMATIC NITRO-ALDEHYDE | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-09-10 | — | — | US | claimed |
| EP-1189885-A1 | PROCESS FOR THE SYNTHESIS OF A-NOR-SECO COMPOUNDS WITH STERANE SKELETON | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2002-03-27 | — | — | EP | claimed |
| WO-2000076968-A1 | PROCESS FOR THE SYNTHESIS OF A-NOR-SECO COMPOUNDS WITH STERANE SKELETON | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2000-12-21 | — | — | WO | claimed |
| WO-2000038634-A1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-07-06 | — | — | WO | claimed |
| US-4456772-A | Process for the preparation of optionally substituted fluoro-nitro-benzaldehydes | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | claimed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | claimed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220257483-A1 | INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL | KRT18, VIM, CDH1 | MAPK1 2440/4885TSHR 4846/4885ERN1 2313/4885 |
| US-20130190500-A1 | PROCESS TO PREPARE 6-CHLORO-3-AMINO-2-(2-HYDROXYPROPYL)-1-AZANAPHTHALENE | AZI2, DNMT1, TPMT | MAPK1 1678/4885TSHR 3185/4885ERN1 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.