Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 15/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469744 | 0.80 | KMT2A (0.45) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2699894 | 0.80 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2494273 | 0.78 | HCN4 (0.45) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2469022 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2471493 | 0.78 | KCNA3 (0.44) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2470694 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2470976 | 0.77 | KCNA3 (0.41) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2469459 | 0.76 | SLC6A9 (0.44) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2471820 | 0.76 | KCNA3 (0.44) | ALDH1A1MEN1KMT2AKCNA3HPGD | |
| SCHEMBL2468588 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AKCNA3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501467-A4 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | BRISTOL MYERS SQUIBB CO (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1501467-A2 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | Bristol-Myers Squibb Company (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003088908-A2 | HETEROCYCLO INHIBITORS OF POTASSIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-10-30 | — | — | WO | disclosed |