Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.62 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948774 | 0.84 | TAAR1 (0.65) | ADRB2TAAR1SLC2A1CASRCHRM2 | |
| SCHEMBL14655805 | 0.82 | TAAR1 (0.67) | ADRB2TAAR1SLC2A1CASRCHRM2 | |
| SCHEMBL2563938 | 0.82 | SLC2A1 (0.60) | ADRB2TAAR1SLC2A1CASRCHRM2 | |
| SCHEMBL2561020 | 0.82 | ADRB2 (0.63) | ADRB2TAAR1SLC2A1ACHECASR | |
| SCHEMBL7151328 | 0.79 | ADRB2 (0.78) | ADRB2CASR | |
| SCHEMBL7151325 | 0.79 | ADRB2 (0.78) | ADRB2CASR | |
| SCHEMBL28244453 | 0.79 | MTNR1A (0.66) | ADRB2TAAR1 | |
| SCHEMBL27922345 | 0.79 | MTNR1A (0.66) | ADRB2TAAR1 | |
| SCHEMBL24925835 | 0.79 | TAAR1 (0.67) | ADRB2TAAR1CHRM2CHRM1CHRM3 | |
| SCHEMBL8592674 | 0.79 | TAAR1 (0.67) | ADRB2TAAR1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701948-A4 | ASSAY FOR ENTACTOGENS | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2009-03-04 | — | — | EP | disclosed |
| EP-1701948-A1 | ASSAY FOR ENTACTOGENS | DADE BEHRING INC. (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005058864-A1 | ASSAY FOR ENTACTOGENS | DADE BEHRING INC. (US) | 2005-06-30 | — | — | WO | disclosed |