Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.75 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.75 |
| ▸ | NQO2 | P16083 | 6/20 | 0.68 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016328 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL1688124 | 0.84 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL4043404 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL30449793 | 0.84 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5350745 | 0.84 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5339739 | 0.83 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL3955906 | 0.83 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5351417 | 0.83 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL14314349 | 0.82 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5340299 | 0.82 | MTNR1A (0.81) | MTNR1AMTNR1BNQO2HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009022062-A1 | NOVEL NAPHTHALENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009022062-A1 | NOVEL NAPHTHALENE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2009-02-19 | — | — | WO | disclosed |