SCHEMBL403239

SCHEMBL403239

C=C(CCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL400291 0.95 TBXAS1 (0.36) TBXAS1
SCHEMBL8468382 0.91 TBXAS1 (0.32) TBXAS1
SCHEMBL1802295 0.90 TBXAS1 (0.34) TBXAS1
SCHEMBL8468384 0.89 TET2 (0.31)
SCHEMBL1803453 0.88 TBXAS1 (0.35) TBXAS1
SCHEMBL399741 0.86 TBXAS1 (0.34) TBXAS1
SCHEMBL8466016 0.86 TBXAS1 (0.34) TBXAS1
SCHEMBL2239507 0.85 TBXAS1 (0.34) TBXAS1
SCHEMBL402993 0.85 TBXAS1 (0.34) TBXAS1
SCHEMBL7754184 0.85 ABCC4 (0.34) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3824005-B1 LIQUID WOUND DRESSING COMPOSITION USTAV MAKROMOLEKULARNI CHEMIE AV CR V V I (CZ) 2023-02-22 EP claimed
EP-3660545-B9 SILICONE HYDROGEL COMPOSITION, SILICONE HYDROGEL LENS, AND METHOD OF MANUFACTURING SILICONE HYDROGEL LENS PEGAVISION CORP (TW) 2021-12-29 EP claimed
EP-3660545-B1 SILICONE HYDROGEL COMPOSITION, SILICONE HYDROGEL LENS, AND METHOD OF MANUFACTURING SILICONE HYDROGEL LENS PEGAVISION CORP (TW) 2021-06-16 EP claimed
US-20210171688-A1 BIOCOMPATIBLE COPOLYMER, CURABLE COMPOSITION, BIOCOMPATIBLE COATING LAYER AND BIOCOMPATIBLE DEVICE INCLUDING THE SAME NATIONAL CENTRAL UNIVERSITY (TW) 2021-06-10 US claimed
EP-3220741-B1 COMPOSITION AND KITS FOR INHIBITION OF PATHOGENIC MICROBIAL INFECTION AND METHODS OF USING THE SAME ROCHAL IND LLC (US) 2021-02-24 EP claimed
EP-3052140-B1 NON-SELF-ADHERENT COATING MATERIALS ROCHAL IND LLC (US) 2019-05-01 EP claimed
EP-1176454-B1 OCULAR LENS MATERIALS AND PROCESS FOR PRODUCING THE SAME MENICON CO LTD (JP) 2003-07-30 EP claimed
EP-0796723-B1 PROCESS FOR PRODUCING OPTIC LENS AND OPTIC LENS OBTAINED THEREBY MENICON CO LTD (JP) 2001-12-05 EP claimed
US-5883152-A HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER NIPPON OIL AND FATS CO., LTD. (JP) 1999-03-16 US claimed
US-20210171688-A1 BIOCOMPATIBLE COPOLYMER, CURABLE COMPOSITION, BIOCOMPATIBLE COATING LAYER AND BIOCOMPATIBLE DEVICE INCLUDING THE SAME NATIONAL CENTRAL UNIVERSITY (TW) 2021-06-10 US disclosed
US-8662663-B2 Hybrid soft contact lens, and production method and hydration treatment method thereof MENICON CO., LTD. (JP) 2014-03-04 US disclosed
US-8101701-B2 having a hydrophilic group and a silicon-containing alkyl group within molecule; lenses with high oxygen permeability independent from the water content may be obtained, wherein the fumaric acid derivatives is superior in compatibility with the hydrophilic monomer used in combination MENICON NECT CO., LTD. (JP) 2012-01-24 US disclosed
US-20080132666-A1 Fumaric Acid Derivatives and Ophthalmic Lenses Using the Same MENICON NECT CO., LTD. (JP) 2008-06-05 US disclosed
EP-1378769-A2 Water-absorptive contact lens and method of producing the same Menicon Co., Ltd. (JP) 2004-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132666-A1 Fumaric Acid Derivatives and Ophthalmic Lenses Using the Same FAH, FH, AQP4 TBXAS1 2741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.