SCHEMBL403250

SCHEMBL403250

C[Si](C)(C)O[Si](CCCO)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL403191 0.92 SMN1; SMN2 (0.33) ALDH1A1
SCHEMBL402410 0.90 LMNA (0.36) ALDH1A1
SCHEMBL30623396 0.88
SCHEMBL15801089 0.84 ALDH1A1 (0.36) ALDH1A1
SCHEMBL12737502 0.83
SCHEMBL12749258 0.82
SCHEMBL15796380 0.80 TSHR (0.46) ALDH1A1
SCHEMBL30623393 0.80 LMNA (0.32) ALDH1A1
SCHEMBL30721455 0.80
SCHEMBL1238146 0.79 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
US-8197841-B2 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED (US) 2012-06-12 US claimed
JP-4732464-B2 2011-07-27 JP claimed
EP-2255228-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS Bausch & Lomb Incorporated (US) 2010-12-01 EP claimed
US-20100069522-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS HUMAX PHARMACEUTICAL S.A. (CO) 2010-03-18 US claimed
EP-1828813-B1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB (US) 2010-02-10 EP claimed
WO-2009117374-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS BAUSCH & LOMB INCORPORATED (US) 2009-09-24 WO claimed
WO-2008057104-A1 USE OF THERMAL REVERSIBLE ASSOCIATIONS FOR ENHANCED POLYMER INTERACTIONS BAUSCH & LOMB INCORPORATED (US) 2008-05-15 WO claimed
WO-2007149083-A1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB INCORPORATED (US) 2007-12-27 WO claimed
EP-1828813-A1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS Bausch & Lomb Incorporated (US) 2007-09-05 EP claimed
US-20070123602-A1 Use of thermal reversible associations for enhanced polymer interactions BAUSCH & LOMB INCORPORATED 2007-05-31 US claimed
US-20060275342-A1 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED 2006-12-07 US claimed
WO-2006068705-A1 POLYMERIZABLE SURFACTANTS AND THEIR USE AS DEVICE FORMING COMONOMERS BAUSCH & LOMB INCORPORATED (US) 2006-06-29 WO claimed
US-20060134169-A1 Polymerizable surfactants and their use as device forming comonomers SALIX PHARMACEUTICALS, INC. 2006-06-22 US claimed
EP-0114894-A1 OXYGEN-PERMEABLE HARD CONTACT LENS HOYA CORPORATION (JP) 1984-08-08 EP claimed
EP-4508115-A1 PREPARATION OF POLYETHER-FUNCTIONAL ORGANOSILICON COMPOUNDS Dow Global Technologies LLC (US) 2025-02-19 EP disclosed
WO-2023201138-A1 PREPARATION OF POLYETHER-FUNCTIONAL ORGANOSILICON COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-10-19 WO disclosed
US-5135297-A Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents BAUSCH & LOMB INCORPORATED (US) 1992-08-04 US disclosed
WO-1992009639-A2 SURFACE-ACTIVE MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed
WO-1992009644-A1 SURFACE MODIFICATION OF POLYMER OBJECTS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO disclosed