Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.61 |
| ▸ | MMP9 | P14780 | 5/20 | 0.61 |
| ▸ | MMP13 | P45452 | 4/20 | 0.61 |
| ▸ | MMP3 | P08254 | 4/20 | 0.61 |
| ▸ | MMP7 | P09237 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.51 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634226 | 0.89 | MCHR1 (0.55) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL5634718 | 0.87 | HCRTR1 (0.47) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14499807 | 0.85 | MMP1 (0.48) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14499810 | 0.85 | MMP1 (0.48) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14499808 | 0.85 | MMP1 (0.48) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14499809 | 0.85 | MMP1 (0.48) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL5636064 | 0.83 | MCHR1 (0.51) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL4033428 | 0.82 | MMP1 (0.59) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL4032630 | 0.77 | ALDH1A1 (0.56) | MMP9LMNAALDH1A1HTT | |
| SCHEMBL5635564 | 0.71 | MMP1 (0.51) | MMP1MMP9MMP13MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |