Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554714 | 1.00 | MAPT (0.41) | MAPTGAAALDH1A1CYP2D6THRB | |
| SCHEMBL21557883 | 0.86 | MGAM (0.35) | MAPTGAAALDH1A1CYP2D6LMNA | |
| SCHEMBL21821549 | 0.85 | MGAM (0.43) | MAPTGAAALDH1A1CYP2D6L3MBTL1 | |
| SCHEMBL26077265 | 0.82 | CYP2D6 (0.44) | GAAALDH1A1CYP2D6THRBATM | |
| SCHEMBL1295911 | 0.82 | CPN1 (0.41) | ALDH1A1 | |
| SCHEMBL19554688 | 0.81 | GPR119 (0.50) | MAPTGAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1575174 | 0.81 | GPR119 (0.50) | MAPTGAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1866738 | 0.80 | CYP2D6 (0.47) | GAAALDH1A1CYP2D6THRBATM | |
| SCHEMBL16530180 | 0.79 | MAPT (0.44) | MAPTGAAALDH1A1CYP2D6THRB | |
| SCHEMBL784840 | 0.79 | GAA (0.44) | MAPTGAAALDH1A1THRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013201-A1 | HETEROCYCLIC GPCR AGONISTS | Prosidion Limited (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007116229-A1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-10-18 | — | — | WO | disclosed |