Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447746 | 0.85 | P2RY12 (0.40) | P2RY12 | |
| SCHEMBL5793386 | 0.85 | P2RY12 (0.40) | P2RY12 | |
| SCHEMBL447747 | 0.71 | HDAC3 (0.40) | P2RY12 | |
| SCHEMBL445438 | 0.71 | P2RY12 (0.51) | P2RY12 | |
| SCHEMBL4033054 | 0.70 | LMNA (0.43) | TAS1R3TAS1R1 | |
| SCHEMBL4255470 | 0.70 | P2RY12 (0.39) | P2RY12 | |
| SCHEMBL15202050 | 0.69 | MAPT (0.47) | TAS1R3TAS1R1 | |
| SCHEMBL446789 | 0.69 | P2RY12 (0.41) | P2RY12 | |
| SCHEMBL446790 | 0.69 | P2RY12 (0.41) | P2RY12 | |
| SCHEMBL4247839 | 0.68 | P2RY12 (0.40) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1611088-B1 | HYDROXAMATES AS THERAPEUTIC AGENTS | PHARMACYCLICS INC (US) | 2009-06-17 | — | — | EP | claimed |