Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 4/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4841372 | 0.87 | TRPA1 (0.39) | ALDH1A1SMN1; SMN2HPGDMMP8MMP3 | |
| SCHEMBL4039661 | 0.82 | TRPA1 (0.40) | ALDH1A1SMN1; SMN2HPGDMMP8TRPA1 | |
| SCHEMBL4033850 | 0.80 | MAPT (0.39) | ALDH1A1POLBKDM4ESMN1; SMN2HPGD | |
| SCHEMBL4841126 | 0.77 | RORC (0.40) | MMP8MMP3TRPA1 | |
| SCHEMBL4843267 | 0.77 | RORC (0.41) | MMP8MMP3TRPA1 | |
| SCHEMBL4839389 | 0.76 | RORC (0.39) | MMP8MMP3TRPA1 | |
| SCHEMBL4033378 | 0.76 | RORC (0.40) | MMP8MMP3TRPA1 | |
| SCHEMBL4841542 | 0.76 | RORC (0.42) | MMP8MMP3TRPA1 | |
| SCHEMBL4840174 | 0.74 | RORC (0.41) | POLBSMN1; SMN2TRPA1 | |
| SCHEMBL4039136 | 0.74 | RORC (0.41) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |