Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.54 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28137761 | 0.89 | PPARA (0.68) | PPARASLC13A5HDAC1HDAC2LTB4R | |
| SCHEMBL3484666 | 0.88 | SLC13A5 (0.45) | PPARASLC13A5HDAC1HDAC2LTB4R | |
| SCHEMBL4037893 | 0.87 | PPARA (0.62) | PPARA | |
| SCHEMBL4033084 | 0.86 | SLC13A5 (0.48) | SLC13A5RXRARXRBFFAR1 | |
| SCHEMBL4035381 | 0.86 | PPARA (0.60) | PPARASLC13A5HDAC1HDAC2LTB4R | |
| SCHEMBL11088495 | 0.82 | PPARA (0.72) | PPARALTB4R | |
| SCHEMBL4035971 | 0.79 | MAP4K4 (0.53) | PPARASLC13A5RXRARXRB | |
| SCHEMBL11096283 | 0.78 | PPARA (0.66) | PPARALTB4R | |
| SCHEMBL11094600 | 0.77 | PPARA (0.74) | PPARA | |
| SCHEMBL3483707 | 0.77 | RXRA (0.43) | SLC13A5RXRARXRBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |