Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 9/20 | 0.51 |
| ▸ | PPARG | P37231 | 8/20 | 0.51 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484417 | 0.86 | PPARA (0.40) | MAP4K4PPARAPPARGSLC13A5RXRA | |
| SCHEMBL4033331 | 0.86 | PPARA (0.66) | PPARAPPARGKDM4EMEN1ALDH1A1 | |
| SCHEMBL3484509 | 0.85 | PPARA (0.56) | MAP4K4PPARAPPARGSLC13A5TSHR | |
| SCHEMBL4035509 | 0.84 | PPARG (0.57) | PPARAPPARGPPARD | |
| SCHEMBL4036545 | 0.84 | PPARG (0.60) | PPARAPPARGMEN1KMT2APPARD | |
| SCHEMBL4033955 | 0.83 | MAP4K4 (0.54) | MAP4K4PPARAPPARGKDM4EMEN1 | |
| SCHEMBL4033084 | 0.82 | SLC13A5 (0.48) | MAP4K4SLC13A5RXRARXRB | |
| SCHEMBL11738947 | 0.81 | PPARG (0.72) | PPARAPPARGMEN1KMT2APPARD | |
| SCHEMBL4035957 | 0.81 | PPARG (0.48) | MAP4K4PPARAPPARGMEN1KMT2A | |
| SCHEMBL4038642 | 0.79 | PPARA (0.54) | MAP4K4PPARAPPARGKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |