SCHEMBL4033466

SCHEMBL4033466

CCCCCCCCCCCCCC(CC1CC1)C(C)=O

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
KMT2A Q03164 1/20 0.51
CA2 P00918 2/20 0.46
GRIK1 P39086 2/20 0.41
GRIK2 Q13002 2/20 0.41
METAP2 P50579 1/20 0.40
GPR84 Q9NQS5 7/20 0.40
FFAR1 O14842 1/20 0.40
MAPT P10636 2/20 0.39
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
TP53 P04637 1/20 0.38
FAAH O00519 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3143573 0.98 ALDH1A1 (0.49) ALDH1A1KMT2ACA2GRIK1GRIK2
SCHEMBL3904244 0.93 ALDH1A1 (0.59) ALDH1A1KMT2ACA2GRIK1GRIK2
SCHEMBL7030297 0.92 ALDH1A1 (0.61) ALDH1A1KMT2ACA2METAP2
SCHEMBL15204003 0.86 GRIK1 (0.53) ALDH1A1KMT2ACA2GRIK1GRIK2
SCHEMBL5379218 0.86 GRIK1 (0.53) ALDH1A1KMT2ACA2GRIK1GRIK2
SCHEMBL2188236 0.82 CA2 (0.53) ALDH1A1KMT2ACA2GRIK1GRIK2
SCHEMBL2946473 0.81 KMT2A (0.40) ALDH1A1KMT2ACA2GRIK1GRIK2
SCHEMBL1038699 0.80 CA2 (0.59) CA2GRIK1GRIK2GPR84FFAR1
SCHEMBL1259905 0.80 CA2 (0.59) CA2GRIK1GRIK2GPR84FFAR1
SCHEMBL1260244 0.80 CA2 (0.59) CA2GRIK1GRIK2GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2766416-B1 PROCESS FOR PREPARING NANOCOMPOSITE TOTAL RES & TECHNOLOGY FELUY (BE) 2018-03-07 EP claimed
EP-0986529-B1 PROCESS FOR THE PREPARATION OF 1,3-DICARBONYL COMPOUNDS EASTMAN CHEM CO (US) 2002-09-25 EP claimed
EP-0940384-B1 Process for the preparation of cyclopropylalkylketones DEGUSSA (DE) 2002-06-12 EP claimed
EP-0864556-B1 Process for the production of high purity cyclopropylmethylketone DEGUSSA (DE) 2001-03-28 EP claimed
EP-0668258-B1 Process for the preparation of 1-cyclopropylalkane-1,3-diones HUELS CHEMISCHE WERKE AG (DE) 1998-04-15 EP claimed
EP-0552586-B1 Process for the production of cyclopropylmethylketone CIBA GEIGY AG (CH) 1995-09-20 EP claimed
WO-2016199763-A1 METHOD FOR PRODUCING 1-CYCLOPROPYLETHYLAMINE OR ACID ADDITION SALT THEREOF 石原産業株式会社 2016-12-15 WO disclosed
EP-1263720-B1 AZETIDINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AVENTIS PHARMA SA (FR) 2009-06-03 EP disclosed
EP-1263720-A1 AZETIDINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Aventis Pharma S.A. (FR) 2002-12-11 EP disclosed
WO-2001064632-A1 AZETIDINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AVENTIS PHARMA S.A. (FR) 2001-09-07 WO disclosed
EP-0864556-B1 Process for the production of high purity cyclopropylmethylketone DEGUSSA (DE) 2001-03-28 EP disclosed
EP-1068169-A1 METHOD FOR CHLORINATING KETONES BASF AKTIENGESELLSCHAFT (DE) 2001-01-17 EP disclosed
EP-0973708-A1 IMPROVED PROCESS FOR PREPARING CYCLOPROPYLACETYLENE BASF AKTIENGESELLSCHAFT (DE) 2000-01-26 EP disclosed
WO-1999047479-A1 METHOD FOR CHLORINATING KETONES BASF AKTIENGESELLSCHAFT (DE) 1999-09-23 WO disclosed
WO-1998040333-A1 IMPROVED PROCESS FOR PREPARING CYCLOPROPYLACETYLENE BASF AKTIENGESELLSCHAFT (DE) 1998-09-17 WO disclosed
EP-0864556-A1 Process for the production of high purity cyclopropylmethylketone HÜLS AKTIENGESELLSCHAFT (DE) 1998-09-16 EP disclosed
EP-0705243-B1 BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES RHONE POULENC AGROCHIMIE (FR) 1998-06-24 EP disclosed
EP-0705243-A1 BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES RHONE-POULENC AGROCHIMIE (FR) 1996-04-10 EP disclosed
WO-1995000476-A1 BETA-AMINOVINYL KETONES, PREPARATION METHOD THEREFOR AND USE THEREOF FOR PREPARING BETA DIKETONES RHONE POULENC AGROCHIMIE (FR) 1995-01-05 WO disclosed
EP-0446133-B1 4H-Pyrrolo[1,2-a]thieno[3,2-f][1,4]diazepine derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1994-09-14 EP disclosed