Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030608 | 0.91 | LPAR1 (0.42) | LPAR1LPAR2LPAR3MAPTMEN1 | |
| SCHEMBL4032925 | 0.88 | LPAR1 (0.42) | LPAR1LPAR2LPAR3MAPTMEN1 | |
| SCHEMBL4031244 | 0.86 | LPAR1 (0.43) | LPAR1LPAR2LPAR3MAPTMEN1 | |
| SCHEMBL4035057 | 0.84 | TP53 (0.41) | LPAR1LPAR2LPAR3MAPTMEN1 | |
| SCHEMBL4035115 | 0.84 | IP6K1 (0.40) | LPAR1LPAR2LPAR3MAPTTP53 | |
| SCHEMBL4034108 | 0.84 | LPAR1 (0.44) | LPAR1LPAR2LPAR3MAPTMEN1 | |
| SCHEMBL4036926 | 0.84 | LPAR1 (0.46) | LPAR1LPAR2LPAR3MAPTMEN1 | |
| SCHEMBL4030964 | 0.84 | HDAC3 (0.39) | LPAR1LPAR2LPAR3MAPTMEN1 | |
| SCHEMBL4029083 | 0.81 | LPAR1 (0.48) | LPAR1LPAR2LPAR3MAPTMEN1 | |
| SCHEMBL4032295 | 0.81 | LPAR1 (0.38) | LPAR1LPAR2LPAR3MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |