Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 2/20 | 0.40 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.40 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035057 | 0.92 | TP53 (0.41) | LPAR1LPAR3LPAR2KDM4EL3MBTL1 | |
| SCHEMBL4034108 | 0.92 | LPAR1 (0.44) | LPAR1LPAR3LPAR2KDM4EALDH1A1 | |
| SCHEMBL4030964 | 0.91 | HDAC3 (0.39) | LPAR1LPAR3LPAR2KDM4EALDH1A1 | |
| SCHEMBL4034159 | 0.89 | LPAR1 (0.44) | IP6K1IP6K3IP6K2LPAR1LPAR3 | |
| SCHEMBL4032925 | 0.88 | LPAR1 (0.42) | LPAR1LPAR3LPAR2TSHRALDH1A1 | |
| SCHEMBL4033684 | 0.87 | NPC1 (0.39) | LPAR1LPAR3LPAR2HTTALDH1A1 | |
| SCHEMBL4027903 | 0.86 | HTT (0.45) | IP6K1IP6K3IP6K2LPAR1LPAR3 | |
| SCHEMBL4032395 | 0.86 | LPAR1 (0.40) | LPAR1LPAR3LPAR2KDM4ECTSA | |
| SCHEMBL4030608 | 0.86 | LPAR1 (0.42) | LPAR1LPAR3LPAR2NPSR1CTSA | |
| SCHEMBL4032913 | 0.85 | LPAR1 (0.42) | LPAR1LPAR3LPAR2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |