SCHEMBL9707035

SCHEMBL9707035

CC(Cc1ccc(O)cc1)NC(=O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 2/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
CTSK P43235 4/20 0.58
CTSL P07711 2/20 0.58
CTSB P07858 2/20 0.58
CTSS P25774 2/20 0.58
OPRM1 P35372 2/20 0.55
OPRD1 P41143 2/20 0.55
OPRK1 P41145 2/20 0.55
ATM Q13315 1/20 0.54
TRPM8 Q7Z2W7 1/20 0.53
ALDH1A1 P00352 1/20 0.53
ALOX15 P16050 1/20 0.53
TACR1 P25103 2/20 0.52
KLK1 P06870 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9782114 1.00 CTRB1 (0.58) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL13534727 0.94 NPC1 (0.65) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL4033719 0.94 NPC1 (0.65) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL13884452 0.90 CTRB1 (0.57) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL14884509 0.90 CTRB1 (0.57) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL10305326 0.89 CTRB1 (0.56) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL15082424 0.89 CTRB1 (0.56) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL12193558 0.89 NPC1 (0.63) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL29137641 0.88 ATM (0.65) CTRB1NPC1RAB9ACTSKCTSL
SCHEMBL14370505 0.88 ATM (0.65) CTRB1NPC1RAB9ACTSKCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111051309-A Triazolotriazine derivatives useful as A2A receptor antagonists 浙江春禾医药科技有限公司 2020-04-21 CN disclosed
CN-1076016-C O-carbamoyl-phenylalaninol compounds, pharmaceutically useful salts thereof and process for preparing the same SK LTD (KR) 2001-12-12 CN disclosed
CN-1204316-A O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same SK LTD (KR) 1999-01-06 CN disclosed
EP-0502498-A1 Phenoxyalkanoic acid derivatives and process for preparation thereof TANABE SEIYAKU CO., LTD. (JP) 1992-09-09 EP disclosed