Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 12/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.30 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.30 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032295 | 0.92 | LPAR1 (0.38) | LPAR1LPAR3LPAR2HTTMAPT | |
| SCHEMBL4031859 | 0.83 | LPAR1 (0.51) | LPAR1LPAR3LPAR2MAPTMEN1 | |
| SCHEMBL4034499 | 0.82 | LPAR1 (0.48) | LPAR1LPAR3LPAR2MAPTMEN1 | |
| SCHEMBL4030949 | 0.82 | LPAR1 (0.53) | LPAR1LPAR3LPAR2MAPTMEN1 | |
| SCHEMBL4033577 | 0.82 | LPAR1 (0.53) | LPAR1LPAR3LPAR2MAPTMEN1 | |
| SCHEMBL4031276 | 0.82 | LPAR1 (0.46) | LPAR1LPAR3LPAR2MAPTABCC3 | |
| SCHEMBL4029159 | 0.81 | LPAR1 (0.47) | LPAR1LPAR3LPAR2 | |
| SCHEMBL4029083 | 0.81 | LPAR1 (0.48) | LPAR1LPAR3LPAR2MAPTMEN1 | |
| SCHEMBL4034108 | 0.81 | LPAR1 (0.44) | LPAR1LPAR3LPAR2MAPTMEN1 | |
| SCHEMBL4034953 | 0.80 | LPAR1 (0.52) | LPAR1LPAR3LPAR2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258484-B1 | NOVEL ISOXAZOLE AND THIAZOLE COMPOUNDS AND USE THEREOF AS DRUGS | KYOWA HAKKO KIRIN CO LTD (JP) | 2009-01-14 | — | — | EP | claimed |