SCHEMBL4033812

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Gsk-204925A SCHEMBL4367870	0.90	PLK1 (1.00)	PLK1PLK3PLK4AURKAJAK2
	SCHEMBL6214432	0.84	PLK1 (0.84)	PLK1PLK3PLK4AURKAJAK2
	SCHEMBL5058239	0.83	PLK1 (1.00)	PLK1PLK3
	SCHEMBL14050260	0.83	PLK1 (0.86)	PLK1PLK3PLK4AURKAJAK2
	SCHEMBL5058276	0.83	PLK1 (0.82)	PLK1PLK3PLK4AURKAJAK2
	SCHEMBL5062225	0.82	PLK1 (1.00)	PLK1PLK3PLK4AURKAJAK2
	SCHEMBL5058210	0.81	PLK1 (1.00)	PLK1PLK3PLK4AURKAJAK2
	SCHEMBL5062636	0.81	PLK1 (0.69)	PLK1PLK3NEK2
	Gsk-312948A SCHEMBL4037298	0.81	PLK1 (1.00)	PLK1PLK3PLK4AURKAJAK2
	SCHEMBL5058253	0.81	PLK1 (0.82)	PLK1PLK3PLK4AURKAJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.