Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28781361 | 0.92 | L3MBTL1 (0.57) | NPC1RAB9AL3MBTL1KMT2AHSP90AA1 | |
| SCHEMBL4036371 | 0.87 | KMT2A (0.57) | NPC1RAB9AL3MBTL1KMT2AHSP90AA1 | |
| SCHEMBL6051170 | 0.74 | KDM4E (0.77) | NPC1RAB9AL3MBTL1KMT2AHSP90AA1 | |
| SCHEMBL8345688 | 0.72 | HSP90AA1 (0.60) | NPC1RAB9AL3MBTL1KMT2AHSP90AA1 | |
| SCHEMBL4037194 | 0.72 | NPC1 (0.81) | NPC1RAB9AL3MBTL1KMT2AHSP90AA1 | |
| SCHEMBL4040116 | 0.72 | KDM4E (0.64) | NPC1RAB9AL3MBTL1KMT2AHSP90AA1 | |
| SCHEMBL50243 | 0.72 | MEN1 (0.55) | NPC1RAB9AKMT2AATMMEN1 | |
| SCHEMBL30365402 | 0.71 | TOP2A (0.57) | RAB9AL3MBTL1KMT2ATOP2AATM | |
| SCHEMBL8345105 | 0.70 | KDM4E (0.60) | L3MBTL1KMT2AHSP90AA1ALOX12MEN1 | |
| SCHEMBL16171231 | 0.70 | TOP2A (0.86) | L3MBTL1KMT2ATOP2AATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079699-A1 | QUINOLINE DERIVATIVES | Envivo Pharmaceuticals, Inc. (US) | 2009-07-22 | — | — | EP | claimed |
| WO-2008014602-A1 | QUINOLINE DERIVATIVES | ENVIVO PHARMACEUTICALS, INC. (US) | 2008-02-07 | — | — | WO | claimed |