Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA4 | P22748 | 4/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.45 |
| ▸ | MMP9 | P14780 | 4/20 | 0.45 |
| ▸ | MMP13 | P45452 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP7 | P09237 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4040817 | 0.85 | MAOB (0.42) | CA1CA2CA9CA4L3MBTL1 | |
| SCHEMBL4035295 | 0.68 | MMP1 (0.60) | CA1CA2CA9CA4MMP1 | |
| SCHEMBL6189627 | 0.68 | MMP1 (0.52) | CA1CA2CA9CA4MMP1 | |
| SCHEMBL10681034 | 0.67 | CA1 (0.54) | CA1CA2CA9CA4MMP1 | |
| SCHEMBL5654242 | 0.65 | MMP1 (0.56) | CA1CA2CA9CA4MMP1 | |
| SCHEMBL6189161 | 0.65 | CACNA2D1 (0.49) | MMP1MMP9MMP13MMP3MMP7 | |
| SCHEMBL14393122 | 0.65 | MMP1 (0.53) | CA1CA2CA9CA4MMP1 | |
| SCHEMBL5324061 | 0.64 | MMP1 (0.58) | CA1CA2CA9CA4MMP1 | |
| SCHEMBL5324461 | 0.64 | MMP1 (0.55) | CA1CA2CA9CA4MMP1 | |
| SCHEMBL3715208 | 0.64 | MMP1 (0.55) | CA1CA2CA9CA4MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |