Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.54 |
| ▸ | PPARA | Q07869 | 10/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FABP2 | P12104 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4035511 | 0.87 | PPARG (0.49) | PPARGPPARAADRB3CYP2C19MEN1 | |
| SCHEMBL3485038 | 0.85 | PPARA (0.58) | PPARGPPARAADRB3CYP1A2CYP3A4 | |
| SCHEMBL4036195 | 0.79 | ALDH1A1 (0.49) | PPARGPPARAADRB3CYP2C19MEN1 | |
| SCHEMBL5322664 | 0.79 | PPARG (0.48) | PPARGPPARAADRB3CYP2C19MEN1 | |
| SCHEMBL11748415 | 0.79 | PPARG (0.45) | PPARGPPARAADRB3CYP2C19MEN1 | |
| SCHEMBL247466 | 0.78 | PPARA (0.68) | PPARGPPARACYP2C19MEN1KMT2A | |
| SCHEMBL12777729 | 0.77 | PPARA (0.68) | PPARGPPARAADRB3CYP2C19MEN1 | |
| SCHEMBL7032523 | 0.76 | PPARA (0.66) | PPARGPPARACYP2C19MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8889149 | 0.76 | PPARA (0.66) | PPARGPPARACYP2C19MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL7026339 | 0.76 | PPARA (0.66) | PPARGPPARACYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |