Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484031 | 0.85 | FBP1 (0.47) | PPARGPPARACYP1A2CYP3A4MAPT | |
| SCHEMBL4036198 | 0.79 | PPARG (0.54) | ALDH1A1KDM4EADRB3PPARGPPARA | |
| SCHEMBL4035511 | 0.76 | PPARG (0.49) | ALDH1A1KDM4EHSD17B10ADRB3PPARG | |
| SCHEMBL21939443 | 0.72 | L3MBTL1 (0.59) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL4033438 | 0.72 | KDM4E (0.53) | ALDH1A1KDM4EHSD17B10MGLLPPARG | |
| SCHEMBL4037904 | 0.72 | KDM4E (0.60) | ALDH1A1KDM4EHSD17B10MGLLPPARG | |
| SCHEMBL29224676 | 0.70 | KDM4E (0.58) | ALDH1A1KDM4EHSD17B10MGLLPPARG | |
| SCHEMBL1045767 | 0.70 | KDM4E (0.62) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL28821563 | 0.70 | ALDH1A1 (0.62) | ALDH1A1KDM4EHSD17B10PPARGPPARA | |
| SCHEMBL6989689 | 0.70 | HSD17B10 (0.62) | ALDH1A1KDM4EHSD17B10PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049107-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | Genfit (FR) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008012470-A2 | SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATION AND USES | GENFIT (FR) | 2008-01-31 | — | — | WO | disclosed |