Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYBB | P04839 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MARK4 | Q96L34 | 9/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928811 | 0.86 | NOX1 (0.39) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL1926716 | 0.82 | NOX1 (0.43) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL1928031 | 0.78 | NOX1 (0.45) | NOX1GAAMAPTMEN1ALOX15 | |
| Hydrochloric Acid SCHEMBL1927109 | 0.77 | NOX1 (0.44) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL4033771 | 0.74 | GRM1 (0.46) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL20456837 | 0.74 | RXFP1 (0.40) | KMT2ALMNARAB9A | |
| SCHEMBL1928409 | 0.72 | MMP1 (0.41) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL1927677 | 0.71 | TP53 (0.44) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL1926577 | 0.70 | CNR2 (0.44) | NOX1GAAMAPTMEN1ALOX15 | |
| SCHEMBL4034451 | 0.70 | NOX1 (0.41) | NOX1GAAMAPTMEN1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379514-B1 | 5-MEMBERED HETEROCYCLES, PREPARATION AND APPLICATION THEREOF AS MEDICAMENTS | IPSEN PHARMA (FR) | 2009-07-15 | — | — | EP | disclosed |
| CN-1284777-C | 5-membered heterocycles, preparation and use thereof as medicine | SOD CONSEILS RECH APPLIC (FR) | 2006-11-15 | — | — | CN | disclosed |
| CN-1535267-A | 5-membered heterocycles, preparation and use thereof as medicine | ��ѧ�о���Ӧ����ѯ��˾ | 2004-10-06 | — | — | CN | disclosed |
| EP-1379514-A2 | 5-MEMBERED HETEROCYCLES, PREPARATION AND APPLICATION THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002083656-A2 | 5-MEMBERED HETEROCYCLES, PREPARATION AND USE THEREOF AS MAO INHIBITORS AND LIPID PEROXIDATION INHIBITORS, PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-10-24 | — | — | WO | disclosed |