Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 4/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667157 | 0.80 | HCAR2 (0.43) | RAB9ADDB1CRBNALDH1A1BRD4 | |
| SCHEMBL4528310 | 0.80 | RAB9A (0.39) | RAB9ADDB1CRBNALDH1A1BRD4 | |
| SCHEMBL22323630 | 0.76 | GSR (0.43) | ALDH1A1GSR | |
| SCHEMBL8418687 | 0.72 | DDB1 (0.48) | RAB9ADDB1CRBNSMN1; SMN2ALDH1A1 | |
| SCHEMBL975944 | 0.72 | GAA (0.39) | RAB9ADDB1CRBNSMN1; SMN2ALDH1A1 | |
| SCHEMBL2957623 | 0.72 | GAA (0.39) | RAB9ADDB1CRBNSMN1; SMN2ALDH1A1 | |
| SCHEMBL7385948 | 0.72 | CYP19A1 (0.41) | RAB9ADDB1CRBNBRD4CREBBP | |
| SCHEMBL27847496 | 0.72 | KMT2A (0.46) | SMN1; SMN2ALDH1A1GSR | |
| SCHEMBL4441195 | 0.70 | GSR (0.39) | ALDH1A1GSR | |
| SCHEMBL7380755 | 0.70 | KMT2A (0.43) | RAB9ADDB1CRBNBRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592436-A4 | COMPOUNDS THAT BIND P2Y sb 2 /sb OR P2Y sb 1 /sb RECEPTORS | KIMBERLY CLARK CO (US) | 2009-09-02 | — | — | EP | disclosed |
| EP-1592436-A2 | COMPOUNDS THAT BIND P2Y sb 2 /sb OR P2Y sb 1 /sb RECEPTORS | Kimberly-Clark Worldwide, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004060907-A2 | COMPOUNDS THAT BIND P2Y2 OR P2Y1 RECEPTORS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2004-07-22 | — | — | WO | disclosed |