Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 6/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 6/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 3/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981724 | 0.89 | CDK5 (0.44) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL2977002 | 0.85 | CDK5 (0.38) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL2972887 | 0.82 | CYP11B2 (0.41) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL2978113 | 0.82 | CDK5 (0.36) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL13888934 | 0.81 | TNF (0.37) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL2981102 | 0.79 | CDK5 (0.43) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL4039246 | 0.78 | CDK5 (0.42) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL2985558 | 0.77 | CDK5 (0.43) | CDK5CDK5R1CCNA2CDK2CDK1 | |
| SCHEMBL4042860 | 0.76 | CDK5 (0.44) | CDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL2981517 | 0.72 | CDK5 (0.43) | CDK5CDK5R1CCNA2CDK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105072-A1 | 2-(Pyridin-2-Yl)-Pyrimidines for Use as Fungicides | BASF SE (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-2010515-A1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007116079-A1 | 2-(PYRIDIN-2-YL)-PYRIMIDINES FOR USE AS FUNGICIDES | BASF SE (DE) | 2007-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105072-A1 | 2-(Pyridin-2-Yl)-Pyrimidines for Use as Fungicides | CBR3, CBR1, CNPY2 | CDK5 1001/4885CDK5R1 1264/4885CCNA2 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.