Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843159 | 0.90 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10POLBKMT2A | |
| SCHEMBL3211208 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10POLBKMT2A | |
| Hydrochloric Acid SCHEMBL9554099 | 0.83 | ALDH1A1 (0.60) | ALDH1A1HPGDHSD17B10POLBKMT2A | |
| SCHEMBL27551104 | 0.82 | PARP1 (0.43) | ALDH1A1HPGDHSD17B10KDM4ECA1 | |
| SCHEMBL4843637 | 0.82 | TSHR (0.44) | ALDH1A1HPGDHSD17B10POLBKMT2A | |
| SCHEMBL27918676 | 0.81 | MAPT (0.48) | ALDH1A1HSD17B10MAPTCA12CA2 | |
| Hydrochloric Acid SCHEMBL4844909 | 0.81 | TSHR (0.43) | ALDH1A1HPGDHSD17B10POLBMAPT | |
| SCHEMBL28125819 | 0.81 | GRIN2D (0.47) | ALDH1A1HPGDHSD17B10POLBKMT2A | |
| SCHEMBL3211336 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HPGDHSD17B10POLBKMT2A | |
| SCHEMBL13728016 | 0.79 | ALDH1A1 (0.64) | ALDH1A1HPGDHSD17B10POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885695-B1 | INDOLINE COMPOUNDS | FOURNIER LAB SA (FR) | 2009-02-25 | — | — | EP | disclosed |