Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3871501 | 0.89 | HDAC1 (0.55) | ALDH1A1HPGDHSD17B10KDM4EHDAC1 | |
| SCHEMBL863993 | 0.86 | HDAC1 (0.63) | ALDH1A1HPGDHSD17B10HDAC1HDAC3 | |
| SCHEMBL11061872 | 0.86 | HDAC1 (0.63) | ALDH1A1HPGDHSD17B10HDAC1HDAC3 | |
| SCHEMBL7373085 | 0.85 | SHMT2 (0.49) | ALDH1A1HPGDHSD17B10KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL29008104 | 0.81 | HDAC1 (0.52) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL1697077 | 0.81 | HDAC1 (0.52) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL10875175 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDHSD17B10POLBKDM4E | |
| SCHEMBL2973683 | 0.80 | HDAC3 (0.47) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL29939818 | 0.80 | HDAC3 (0.45) | ALDH1A1HPGDHSD17B10HDAC1HDAC3 | |
| SCHEMBL6201094 | 0.80 | MAPT (0.52) | ALDH1A1HPGDHSD17B10MEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1172929-C | substituted indoles | ���ĵ�˹ҩ��¹�����˾ | 2004-10-27 | — | — | CN | claimed |
| CN-1168727-C | Substituted benzimidazole | ���ĵ�˹ҩ��¹�����˾ | 2004-09-29 | — | — | CN | claimed |
| WO-2020044206-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS FOR USE IN THE TREATMENT CANCER | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-03-05 | — | — | WO | disclosed |
| EP-2705039-A2 | BROMODOMAIN INHIBITORS AND USES THEREOF | Constellation Pharmaceuticals, Inc. (US) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012151512-A2 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2012-11-08 | — | — | WO | disclosed |
| CN-1172929-C | substituted indoles | ���ĵ�˹ҩ��¹�����˾ | 2004-10-27 | — | — | CN | disclosed |
| CN-1168727-C | Substituted benzimidazole | ���ĵ�˹ҩ��¹�����˾ | 2004-09-29 | — | — | CN | disclosed |
| CN-1379772-A | Substituted indoles for modulating NF kappa B activity | AVENTIS PHARMA GMBH (DE) | 2002-11-13 | — | — | CN | disclosed |
| CN-1356995-A | Substituted benzimidazole | AVENTIS PHARMA GMBH (DE) | 2002-07-03 | — | — | CN | disclosed |