Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.61 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1840673 | 0.90 | MKNK1 (0.56) | FFAR4MKNK1MKNK2NPC1LMNA | |
| SCHEMBL4039531 | 0.88 | FFAR4 (0.55) | FFAR4MKNK1MKNK2NPC1LMNA | |
| SCHEMBL4039020 | 0.85 | FFAR4 (0.48) | FFAR4MAPTRXFP1LTB4RTBXAS1 | |
| SCHEMBL27513663 | 0.84 | FFAR4 (0.58) | FFAR4NPC1LMNAPKMMAPT | |
| SCHEMBL4037637 | 0.82 | TBXAS1 (0.50) | MAPTRXFP1TBXAS1FFAR1HSD17B10 | |
| SCHEMBL16479585 | 0.81 | CASP3 (0.54) | FFAR4MKNK1MKNK2NPC1MAPT | |
| SCHEMBL1842380 | 0.81 | MKNK1 (0.55) | FFAR4MKNK1MKNK2NPC1LMNA | |
| SCHEMBL17795639 | 0.80 | MAPT (0.52) | MKNK1MKNK2NPC1LMNAMAPT | |
| SCHEMBL13526973 | 0.79 | MKNK1 (0.46) | FFAR4MKNK1MKNK2NPC1LMNA | |
| SCHEMBL6069860 | 0.78 | P4HTM (0.58) | FFAR4NPC1LMNAPKMFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |