Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032461 | 0.87 | CCR5 (0.32) | CCR5 | |
| SCHEMBL3925985 | 0.83 | CCR5 (0.34) | CCR5 | |
| SCHEMBL1800874 | 0.78 | CCR5 (0.32) | CCR5 | |
| SCHEMBL4035595 | 0.77 | CCR5 (0.38) | CCR5 | |
| SCHEMBL2999337 | 0.75 | — | — | |
| SCHEMBL1800729 | 0.75 | CYP2D6 (0.50) | — | |
| SCHEMBL3927335 | 0.73 | POLB (0.39) | — | |
| SCHEMBL1801638 | 0.73 | CRBN (0.46) | — | |
| SCHEMBL1802377 | 0.73 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL1800759 | 0.72 | HRH3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730144-B1 | SUBSTITUTED 1,4,8-TRIAZASPIRO¬4.5 DECAN-2-ONE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2009-06-10 | — | — | EP | claimed |