Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | DRD1 | P21728 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 4/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.52 |
| ▸ | MC3R | P41968 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | MLNR | O43193 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4039786 | 0.99 | LMNA (0.51) | DRD2HTR1ADRD1HRH1DRD3 | |
| SCHEMBL4040369 | 0.94 | LMNA (0.48) | DRD2HTR1ADRD1HRH1DRD3 | |
| Hydrochloric Acid SCHEMBL4041643 | 0.93 | LMNA (0.49) | DRD2HTR1ADRD1HRH1DRD3 | |
| SCHEMBL4038832 | 0.93 | CYP3A4 (0.52) | DRD2HTR1ADRD1HRH1DRD3 | |
| SCHEMBL6338922 | 0.93 | CYP3A4 (0.52) | DRD2HTR1ADRD1HRH1DRD3 | |
| Hydrochloric Acid SCHEMBL4036505 | 0.92 | LMNA (0.53) | DRD2HTR1ADRD1HRH1DRD3 | |
| SCHEMBL4037897 | 0.89 | RAD52 (0.41) | DRD2HTR1ADRD1HRH1DRD3 | |
| Hydrochloric Acid SCHEMBL4039720 | 0.89 | CHRM2 (0.39) | DRD2HTR1ADRD1HRH1DRD3 | |
| Hydrochloric Acid SCHEMBL4035920 | 0.88 | RAD52 (0.43) | DRD2HTR1ADRD1HRH1DRD3 | |
| SCHEMBL6333796 | 0.88 | MLNR (0.38) | DRD2HTR1ADRD1HRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284977-B1 | THIENODIBENZOAZULENE COMPOUNDS AS TUMOR NECROSIS FACTOR INHIBITORS | GLAXOSMITHKLINE ZAGREB (HR) | 2009-06-24 | — | — | EP | claimed |
| US-7569575-B2 | Formed via intermediates which are reactive with nucleophiles | SANTARIS PHARMA A/S (DK) | 2009-08-04 | — | — | US | disclosed |
| EP-1501848-B1 | SYNTHESIS OF LOCKED NUCLEIC ACID DERIVATIVES | SANTARIS PHARMA AS (DK) | 2007-08-08 | — | — | EP | disclosed |
| US-20040014959-A1 | Synthesis of locked nucleic acid derivatives | SANTARIS PHARMA A/S (DK) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014959-A1 | Synthesis of locked nucleic acid derivatives | NSUN3, RNGTT, NSUN2 | DRD2 4288/4885HTR1A 3547/4885DRD1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.