Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 18/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4032546 | 1.00 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4033360 | 1.00 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4035814 | 1.00 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4036731 | 1.00 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4038511 | 0.89 | HSD11B1 (0.43) | HSD11B1 | |
| SCHEMBL4037368 | 0.75 | CCR1 (0.39) | — | |
| SCHEMBL16276190 | 0.65 | SMN1; SMN2 (0.68) | — | |
| SCHEMBL1950324 | 0.65 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL1950325 | 0.65 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL15139477 | 0.65 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |