Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 10/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033360 | 0.89 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4035814 | 0.89 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4037786 | 0.89 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4036731 | 0.89 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4032546 | 0.89 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL4035864 | 0.71 | MEN1 (0.44) | DRD4 | |
| SCHEMBL1384325 | 0.67 | MGLL (0.49) | GRIN2C | |
| SCHEMBL4037368 | 0.66 | CCR1 (0.39) | — | |
| SCHEMBL8239827 | 0.63 | DRD1 (0.58) | GRIN2C | |
| SCHEMBL15139389 | 0.61 | HSD11B1 (1.00) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592389-B1 | PIPERAZINE-2-CARBOXAMIDE DERIVATIVES | SERONO LAB (CH) | 2009-04-22 | — | — | EP | claimed |